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2829

Brad Merrill

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Brad Merrill
CEO & Co-Founder of
Syntax Bio (2021)
About

Brad Merrill, Ph.D. is Co-Founder and Head of Innovation at Syntax Bio, a Chicago-based synthetic biology company programming the next generation of cell therapies using its proprietary CRISPR-based Cellgorithm platform.

Before founding

Brad earned his Ph.D. from the University of California, San Diego in 1999 and completed postdoctoral training at the University of Chicago and Rockefeller University, before joining UIC as a Professor of Biochemistry and Molecular Genetics where he spent two decades studying pluripotent stem cell biology.

Founder Insights

Brad's lab pioneered CRISPR-based lineage tracing tools that introduced temporally controlled genetic perturbation, culminating in the proGuide system published in Molecular Cell and Science Advances. He was awarded the iBio iCON Innovator Award in recognition of his scientific contributions to regenerative medicine.

Experience

Brad co-founded Syntax Bio alongside former PhD student Ryan Clarke, translating over two decades of academic stem cell research into a venture-backed biotech company that has filed 7 patents and attracted investors including Astellas Venture Management, Illumina Ventures, DCVC Bio, and Draper Associates.

Scale & Impact

Syntax Bio has raised over $25 million in total funding, established collaborations with Mayo Clinic and Breakthrough T1D, and is advancing pancreatic beta cell therapies that could eliminate the need for insulin injections in type 1 diabetes patients.

2829

Brad Merrill

Syntax Bio
Co-Founder
Logo
Brad Merrill

Company(s)

Syntax Bio

Industry

Healthtech & Biotech

Year Founded

2021

Stage/Funding

Series A • $25M

Company Location

us

Connect

About

Brad Merrill, Ph.D. is Co-Founder and Head of Innovation at Syntax Bio, a Chicago-based synthetic biology company programming the next generation of cell therapies using its proprietary CRISPR-based Cellgorithm platform.

Before founding

Brad earned his Ph.D. from the University of California, San Diego in 1999 and completed postdoctoral training at the University of Chicago and Rockefeller University, before joining UIC as a Professor of Biochemistry and Molecular Genetics where he spent two decades studying pluripotent stem cell biology.

Founder Insights

Brad's lab pioneered CRISPR-based lineage tracing tools that introduced temporally controlled genetic perturbation, culminating in the proGuide system published in Molecular Cell and Science Advances. He was awarded the iBio iCON Innovator Award in recognition of his scientific contributions to regenerative medicine.

Experience

Brad co-founded Syntax Bio alongside former PhD student Ryan Clarke, translating over two decades of academic stem cell research into a venture-backed biotech company that has filed 7 patents and attracted investors including Astellas Venture Management, Illumina Ventures, DCVC Bio, and Draper Associates.

Scale & Impact

Syntax Bio has raised over $25 million in total funding, established collaborations with Mayo Clinic and Breakthrough T1D, and is advancing pancreatic beta cell therapies that could eliminate the need for insulin injections in type 1 diabetes patients.

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